Best PCIe Audio Interfaces for Professional 2025

Perfect pcie audio interfaces for professional - easy to play and learn on

Last updated: October 15, 2025 • Next update: October 22, 2025

PRICE RANGES: Under $2,000

SKILL LEVELS: For Intermediate For Professional For Advanced

GENRES & STYLES: For Desktop Studio For Professional Recording For Low Latency For High Channel Count

BRANDS: RME

Lynx Studio AES-16e PCI Express - Professional Music Instrument Photo

⭐ 4.5/5 (56 reviews)

Sound:

9/10

Build:

8/10

Value:

6/10

Lynx Studio AES-16e PCI Express

by Lynx Studio

Low Latency High Channel Count Professional Recording

Key Feature:

• High-speed PCIe bus connection

✓ PROS

• High-speed PCIe bus connection
• Professional studio standard

✗ CONS

• Professional installation required
• No portability for mobile recording

Lynx Studio AES-16e PCI ExpressPCI Express Card16 Channels of AES / EBU digital I / O192 kHz / 24-bit single-wire and...

⭐ 4.5/5 (56 reviews)

Sound:

9/10

Build:

8/10

Value:

6/10

Art. 225515

$1,066

Buy at Thomann View Details

Marian Clara A XLR - Professional Music Instrument Photo

⭐ 4.8/5 (3 reviews)

Sound:

8/10

Build:

9/10

Value:

7/10

Marian Clara A XLR

by Marian

Desktop Studio Low Latency Professional Recording

Key Feature:

• High-speed PCIe bus connection

✓ PROS

• High-speed PCIe bus connection
• Professional studio standard

✗ CONS

• Professional installation required
• Requires PCIe slot availability

Marian Clara A XLR16-Channel PCIe Audio Interface24 bit / 192 KHzAuto-mute of the analogue outputs at system...

⭐ 4.8/5 (3 reviews)

Sound:

8/10

Build:

9/10

Value:

7/10

Art. 605130

$855

Buy at Thomann View Details

RME HDSPe Madi FX - Professional Music Instrument Photo

⭐ 4.8/5 (15 reviews)

Sound:

10/10

Build:

10/10

Value:

8/10

RME HDSPe Madi FX

by RME

Low Latency High Channel Count Professional Recording

Key Feature:

• Ultra-low latency performance

✓ PROS

• High-speed PCIe bus connection
• Professional studio standard

✗ CONS

• Professional installation required
• No portability for mobile recording

RME HDSPe Madi FXPCI Express Sound CardMADI: 194 input and 194 output channelsAnalogue output: 2 channels (6.3 mm...

⭐ 4.8/5 (15 reviews)

Sound:

10/10

Build:

10/10

Value:

8/10

Art. 280212

$1,484

Buy at Thomann View Details

Focusrite RedNet PCIeNX - Professional Music Instrument Photo

⭐ 4.4/5 (3 reviews)

Sound:

9/10

Build:

8/10

Value:

7/10

Focusrite RedNet PCIeNX

by Focusrite

Low Latency Professional Recording Desktop Studio

Key Feature:

• Ultra-low latency performance

✓ PROS

• Direct computer integration
• High-speed PCIe bus connection

✗ CONS

• No portability for mobile recording
• Requires PCIe slot availability

Focusrite RedNet PCIeNXPCIe DANTE Audio InterfaceUp to 256 x 256 audio channels at 24-bit / 96 kHz or 128 x 128 audio...

⭐ 4.4/5 (3 reviews)

Sound:

9/10

Build:

8/10

Value:

7/10

Art. 568307

$1,731

Buy at Thomann View Details

RME HDSPe MADI - Professional Music Instrument Photo

⭐ 4.9/5 (23 reviews)

Sound:

10/10

Build:

10/10

Value:

8/10

RME HDSPe MADI

by RME

Low Latency High Channel Count Professional Recording

Key Feature:

• Ultra-low latency performance

✓ PROS

• Professional studio standard
• Ultra-low latency performance

✗ CONS

• Requires PCIe slot availability
• Expensive high-end models

RME HDSPe MADIPCI Express Card With MADI I / O128 ChannelsUp to 192 kHzAll input and playback channels can be...

⭐ 4.9/5 (23 reviews)

Sound:

10/10

Build:

10/10

Value:

8/10

Art. 114255

$1,319

Buy at Thomann View Details

RME HDSPe AoX-M - Professional Music Instrument Photo

⭐ 4.7/5 (10 reviews)

Sound:

8/10

Build:

10/10

Value:

7/10

RME HDSPe AoX-M

by RME

High Channel Count Desktop Studio Low Latency

Key Feature:

• Direct computer integration

✓ PROS

• High channel count capability
• Direct computer integration

✗ CONS

• No portability for mobile recording
• Requires PCIe slot availability

RME HDSPe AoX-MPCIe x4 Audio Interface with Milan Compatible AVB512/256/128 Channels at 48/96/192 kHz sampling...

⭐ 4.7/5 (10 reviews)

Sound:

8/10

Build:

10/10

Value:

7/10

Art. 593946

$1,506

Buy at Thomann View Details

Lynx Studio E44 - Professional Music Instrument Photo

⭐ 4.5/5 (10 reviews)

Sound:

8/10

Build:

8/10

Value:

8/10

Lynx Studio E44

by Lynx Studio

Low Latency Professional Recording High Channel Count

Key Feature:

• Ultra-low latency performance

✓ PROS

• High channel count capability
• Ultra-low latency performance

✗ CONS

• Limited to desktop computers
• Expensive high-end models

Lynx Studio E44PCI Express Audio CardFour-channel A / D and D / A conversionFour channels AES3 or S / PDIF I /...

⭐ 4.5/5 (10 reviews)

Sound:

8/10

Build:

8/10

Value:

8/10

Art. 360084

$1,440

Buy at Thomann View Details

Lynx Studio E22 - Professional Music Instrument Photo

⭐ 4.8/5 (31 reviews)

Sound:

8/10

Build:

8/10

Value:

7/10

Lynx Studio E22

by Lynx Studio

Low Latency Desktop Studio High Channel Count

Key Feature:

• Professional studio standard

✓ PROS

• Direct computer integration
• High-speed PCIe bus connection

✗ CONS

• Limited to desktop computers
• No portability for mobile recording

Lynx Studio E22PCI Express Audio CardTwo-channel A / D and D / A conversionTwo channels AES3 or S / PDIF I /...

⭐ 4.8/5 (31 reviews)

Sound:

8/10

Build:

8/10

Value:

7/10

Art. 360083

$1,176

Buy at Thomann View Details

RME HDSPe RayDAT - Professional Music Instrument Photo

⭐ 4.9/5 (22 reviews)

Sound:

8/10

Build:

9/10

Value:

7/10

RME HDSPe RayDAT

by RME

High Channel Count Low Latency Professional Recording

Key Feature:

• High-speed PCIe bus connection

✓ PROS

• Professional studio standard
• High channel count capability

✗ CONS

• Professional installation required
• No portability for mobile recording

RME HDSPe RayDAT, 72-channel ADAT / AES PCI Express CardHDSPe RayDAT is a multi-channel, multi-format and multi-tasking...

⭐ 4.9/5 (22 reviews)

Sound:

8/10

Build:

9/10

Value:

7/10

Art. 208766

$659

Buy at Thomann View Details

RME HDSPe AoX-D - Professional Music Instrument Photo

#10

⭐ 4.6/5 (18 reviews)

Sound:

8/10

Build:

9/10

Value:

6/10

RME HDSPe AoX-D

by RME

Professional Recording Low Latency Desktop Studio

Key Feature:

• High channel count capability

✓ PROS

• Professional studio standard
• Direct computer integration

✗ CONS

• No portability for mobile recording
• Limited to desktop computers

RME HDSPe AoX-DPCIe x4 Audio Interface with DANTE and MADI512/256/128 channels at 48/96/192 kHz sampling rateSteady...

⭐ 4.6/5 (18 reviews)

Sound:

8/10

Build:

9/10

Value:

6/10

Art. 593948

$1,946

Buy at Thomann View Details

RME HDSPe AES - Professional Music Instrument Photo

#11

⭐ 4.7/5 (49 reviews)

Sound:

9/10

Build:

9/10

Value:

7/10

RME HDSPe AES

by RME

Professional Recording Desktop Studio Low Latency

Key Feature:

• High channel count capability

✓ PROS

• Direct computer integration
• Ultra-low latency performance

✗ CONS

• Professional installation required
• Limited to desktop computers

RME HDSPe AES
Audio Interface
PCI Express
Up to 192 kHz
16 I/O
8x AES/EBU I/O
2x MIDI I/O
Wordclock I/O
Total Mix
For WIN/MAC

⭐ 4.7/5 (49 reviews)

Sound:

9/10

Build:

9/10

Value:

7/10

Art. 214127

$989

Buy at Thomann View Details

Avid HDX PCIe Card only - Professional Music Instrument Photo

#12

⭐ 4.7/5 (20 reviews)

Sound:

9/10

Build:

9/10

Value:

7/10

Avid HDX PCIe Card only

by Avid

Desktop Studio Professional Recording High Channel Count

Key Feature:

• High channel count capability

✓ PROS

• High-speed PCIe bus connection
• Professional studio standard

✗ CONS

• Professional installation required
• Limited to desktop computers

Avid HDX Core Card only, Pro Tools HDX PCIe Card, For expansion of existing HDX systems or using in conjunction with...

⭐ 4.7/5 (20 reviews)

Sound:

9/10

Build:

9/10

Value:

7/10

Art. 398487

$6,489

Buy at Thomann View Details

RME HDSPe AIO Pro - Professional Music Instrument Photo

#13

⭐ 4.8/5 (27 reviews)

Sound:

8/10

Build:

8/10

Value:

7/10

RME HDSPe AIO Pro

by RME

Desktop Studio Low Latency Professional Recording

Key Feature:

• Direct computer integration

✓ PROS

• High channel count capability
• High-speed PCIe bus connection

✗ CONS

• Requires PCIe slot availability
• Expensive high-end models

RME HDSPe AIO Pro30-Channel PCI Express Audio Interface192 kHz / 24 BitADI-2 Pro converter AK5572 and 2 x AK4490The...

⭐ 4.8/5 (27 reviews)

Sound:

8/10

Build:

8/10

Value:

7/10

Art. 500503

$791

Buy at Thomann View Details

ESI MAYA44 eX - Professional Music Instrument Photo

#14

⭐ 4.6/5 (8 reviews)

Sound:

9/10

Build:

8/10

Value:

8/10

ESI MAYA44 eX

by ESI

High Channel Count Professional Recording Low Latency

Key Feature:

• High channel count capability

✓ PROS

• High channel count capability
• High-speed PCIe bus connection

✗ CONS

• Limited to desktop computers
• Professional installation required

ESI MAYA44 eXPCIe Audio InterfaceWith 4 analogue input and 4 analogue output channels (simultaneously)1 Microphone...

⭐ 4.6/5 (8 reviews)

Sound:

9/10

Build:

8/10

Value:

8/10

Art. 411612

$153

Buy at Thomann View Details

ESI Juli@ eX - Professional Music Instrument Photo

#15

⭐ 4.9/5 (47 reviews)

Sound:

7/10

Build:

7/10

Value:

7/10

ESI Juli@ eX

by ESI

Desktop Studio Professional Recording High Channel Count

Key Feature:

• Ultra-low latency performance

✓ PROS

• Ultra-low latency performance
• Professional studio standard

✗ CONS

• Requires PCIe slot availability
• Limited to desktop computers

ESI Juli@ eXPCIe Audio InterfaceSabre ESS converter with 32bit / 192kHzEWDM driver for low latencyInterchangeable I/O...

⭐ 4.9/5 (47 reviews)

Sound:

7/10

Build:

7/10

Value:

7/10

Art. 623190

$208

Buy at Thomann View Details

How to Choose the Best PCIe Audio Interfaces

Budget Planning

• Under $200: Entry-level
• $200-$500: Intermediate
• $500-$1000: Advanced
• $1000+: Professional

Quality Check

• Sound clarity & tone
• Build materials & finish
• Hardware durability
• Overall craftsmanship

Key Features

• Your musical style
• Skill level match
• Intended use case
• Brand reputation

Frequently Asked Questions

Key factors include build quality, sound characteristics, playability, brand reputation, warranty coverage, and value for money. Consider your musical style, skill level, and intended use to find the best match.

Budget depends on your needs and experience level. Beginners can find quality options for $200-500, intermediate players should consider $500-1500 range, while professionals often invest $1500+ for premium features.

Higher-priced pcie audio interfaces typically offer better materials, craftsmanship, and performance. They're worth it if you're serious about music, perform regularly, or need professional-grade features.

Top brands combine quality, innovation, and reliability. We evaluate brands based on build quality, sound performance, durability, and customer satisfaction to recommend the best options for different budgets.

Both have advantages. Online offers better prices and selection, while stores allow hands-on testing. We recommend researching online first, then testing in stores if possible. Many online retailers offer excellent return policies.

Best PCIe Audio Interfaces for Professional 2025

Lynx Studio AES-16e PCI Express

Marian Clara A XLR

RME HDSPe Madi FX

Focusrite RedNet PCIeNX

RME HDSPe MADI

RME HDSPe AoX-M

Lynx Studio E44

Lynx Studio E22

RME HDSPe RayDAT

RME HDSPe AoX-D

RME HDSPe AES

Avid HDX PCIe Card only

RME HDSPe AIO Pro

ESI MAYA44 eX

ESI Juli@ eX

How to Choose the Best PCIe Audio Interfaces

Budget Planning

Quality Check

Key Features

Frequently Asked Questions

What should I look for when buying pcie audio interfaces?

How much should I spend on pcie audio interfaces?

Are expensive pcie audio interfaces worth the investment?

What are the best brands for pcie audio interfaces?

Should I buy pcie audio interfaces online or in-store?

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