AudioFuAudioFu Chart · October 2026
Best Sequential General Synthesizers 2026
The top pick is Sequential Trigon-6 49-Key 6-Voice Polyphonic Synthesizer ($4,145). Sequential Fourm gives you the most for the money at $895. Ranked by the AudioFu Index from 12 models, prices checked every night.
Last updated: October 11, 2026
Top 10
Full detail for the 10 highest AudioFu Index scores. Every other model is listed below.
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Sequential Trigon-6 49-Key 6-Voice Polyphonic Synthesizer
Trigon-6 · Sequential
33 for sale on Reverb1 finish at Thomann
- Weight9.5 kg
- Keys49 keys
- Key actionSemi-weighted keys
The Trigon-6 is a powerhouse for sound design and classic analog tones. It's a serious instrument for producers and synth enthusiasts craving that vintage Sequential sound, particularly if you're into pads, basses, and leads with a raw, unfiltered edge. The keybed is a nice surprise, but the limited keys are a consideration.
Pros
- Discrete VCOs deliver a fat, complex analog warmth.
- Semi-weighted keys offer nuanced velocity and aftertouch expression.
- Discrete filter design provides exceptional resonance and character.
Cons
- The 49-key keyboard limits performance for complex pieces.
- Premium-priced, a significant investment for many musicians.
65AudioFu
Index↑ 11.1%since Aug 14$3,730 · Aug 14$4,145 now$4,145€3,699 at Thomann · in stockCheck price ↗ -
Sequential Pro 3 37-Key 3-Voice Monophonic / Paraphonic Synthesizer
Pro 3 · Sequential
37 for sale on Reverb2 finishes at Thomann
- Weight7.25 kg
The Pro 3 is a serious instrument for sound designers and synth enthusiasts craving classic Sequential character with modern flexibility. Its multiple filter options and powerful sequencing capabilities allow for incredible sonic depth, making it a fantastic choice for those wanting a focused, expressive monophonic or paraphonic voice – it’s a powerhouse for lead lines, bass, and experimental soundscapes.
Pros
- Exceptional filter flexibility with Prophet-6, OB-6, and Ladder options
- Deep modulation matrix unlocks complex and evolving sounds
- Powerful 16-track sequencer facilitates intricate compositions
Cons
- Monophonic/paraphonic limits versatility for full chords
- Relatively heavy, making portability a consideration
64AudioFu
Index↑ 3.8%since Aug 14$2,341 · Aug 14$2,431 now$2,431€2,169 at Thomann · in stockCheck price ↗ -
Sequential Prophet-6 49-Key 6-Voice Polyphonic Synthesizer
Prophet 6 · Sequential
30 for sale on Reverb1 finish at Thomann
- Weight9.3 kg
- Key actionSemi-weighted keys
The Prophet 6 delivers that classic Sequential sound – lush, warm, and undeniably analog. It's a fantastic choice for synth enthusiasts and sound designers craving a vintage vibe with modern sequencing capabilities; its relatively compact size makes it studio-friendly, though its weight is something to consider.
Pros
- Rich, analog warmth thanks to discrete VCOs and filter
- Excellent build quality with sturdy metal chassis and solid keybed
- Versatile arpeggiator and step sequencer inspire creative sequencing
Cons
- Limited polyphony (6 voices) restricts complex layering
- Keybed action, while decent, lacks the nuance of high-end weighted action
59AudioFu
Index↑ 12.2%since Aug 14$3,793 · Aug 14$4,257 now$4,257€3,799 at Thomann · in stockCheck price ↗ -
Sequential Prophet Rev2 61-Key 8-Voice Polyphonic Synthesizer
Prophet REV2-8 HeadphoneBundle · Sequential
27 for sale on Reverb2 finishes at Thomann
- Weight9.3 kg
This synth packs a lot of original Prophet sound into a portable package. You get eight voices and two digital oscillators per voice, plus the classic Curtis filter and four LFOs. The step sequencer and arpeggiator let you build patterns quickly, and the 512 factory presets cover many styles. It fits well in a studio or on the road, though you'll need to buy extra cards to hit 16 voices.
Pros
- 8-voice polyphony with two digital oscillators per voice
- Original Prophet 4 LFOs and Curtis lowpass filter
- 512 factory presets plus fully editable user programs
Cons
- No built-in reverb or delay effects mentioned
- Expandable to 16 voices requires an optional card
57AudioFu
Index↑ 13.9%since Aug 17$2,655 · Aug 17$3,025 now$3,025€2,699 at Thomann · in stockCheck price ↗ -
Sequential Prophet-10 61-Key 10-Voice Polyphonic Synthesizer
Prophet 10 · Sequential
28 for sale on Reverb1 finish at Thomann
- Weight14.06 kg
The Prophet 10 is a beautiful, authentic recreation of the classic Prophet-5 architecture, expanded for modern use. It delivers that instantly recognizable, warm analog tone with incredible depth, and the Vintage Knob makes tweaking a breeze. This is a dream synth for serious analog enthusiasts and sound designers seeking a truly vintage vibe.
Pros
- Exceptional CEM 3340 oscillator warmth; truly vintage Prophet sound
- Highly flexible filter options emulate Prophet-5 revisions
- Velocity-sensitive Fatar keyboard offers excellent playability and expression
Cons
- High-end price point places it out of reach for many musicians
- Limited modulation options compared to more modern synthesizers
57AudioFu
Index↑ 4.0%since Aug 14$5,042 · Aug 14$5,243 now$5,243€4,679 at Thomann · in stockCheck price ↗ -
Sequential Take 5 44-Key 5-Voice Compact Polyphonic Synthesizer
Take 5 · Sequential
27 for sale on Reverb1 finish at Thomann
- Weight7.7 kg
The Take 5 is a brilliant, instantly playable analog polysynth that captures the essence of the Prophet 5. It's a fantastic choice for synth enthusiasts, sound designers, and anyone wanting that warm, vintage Sequential vibe without the vintage price tag. The onboard effects are surprisingly good, making it a complete performance instrument.
Pros
- Dual VCOs offer incredible sonic complexity and flexibility.
- Prophet 5 filter delivers that classic, creamy Sequential sound.
- Extensive effects section provides immediate, inspiring creative options.
Cons
- 44-key keyboard limits playing range for complex arrangements.
- The sequencer, while capable, isn't as intuitive as dedicated units.
56AudioFu
Index↑ 5.3%since Aug 14$1,680 · Aug 14$1,769 now$1,769€1,579 at Thomann · in stockCheck price ↗ -
Sequential Prophet-5 61-Key 5-Voice Polyphonic Synthesizer
Prophet 5 · Sequential
28 for sale on Reverb1 finish at Thomann
- Weight14.06 kg
The new Prophet 5 is a stunning recreation of a legend. It captures the classic Prophet 5 sound with some modern refinements, like the selectable filter versions. This is a dream synth for serious sound designers, vintage enthusiasts, and anyone wanting that quintessential 80s analog vibe.
Pros
- Exceptional CEM 3340 oscillator warmth and character
- Vintage Knob offers deep, nuanced sound shaping possibilities
- Velocity-sensitive Fatar keyboard delivers superb playability and expression
Cons
- High-end price point makes it a significant investment
- Limited modulation options compared to modern synths
56AudioFu
Index↑ 6.8%since Aug 14$3,984 · Aug 14$4,253 now$4,253€3,795 at Thomann · in stockCheck price ↗ -
Sequential OB-6 49-Key 6-Voice Polyphonic Synthesizer
OB-6 · Sequential
14 for sale on Reverb1 finish at Thomann
- Weight9.5 kg
- Key actionWeighted keys
The OB-6 is a fantastic tribute to Oberheim's legacy, offering that classic, fat SEM sound in a modern, polyphonic package. It’s perfect for sound designers, vintage synth enthusiasts, and anyone craving a truly unique analog voice. While it's a premium-priced instrument, the sonic character and sequencing capabilities are hard to match.
Pros
- Classic Oberheim SEM filter delivers a uniquely warm, resonant tone
- Discrete VCOs provide excellent stability and harmonic richness
- Comprehensive arpeggiator and sequencer inspire creative sequencing
Cons
- Premium-priced, a significant investment for most musicians
- Lightly weighted keys lack the feel of a professional stage piano
52AudioFu
Index↑ 13.0%since Aug 14$3,764 · Aug 14$4,253 now$4,253€3,795 at Thomann · in stockCheck price ↗ -
Sequential Prophet Rev2 61-Key 16-Voice Polyphonic Synthesizer
Prophet REV2-16 · Sequential
17 for sale on Reverb1 finish at Thomann
- Weight9.3 kg
The REV2-16 is a powerhouse of analog synthesis, delivering the sound and feel of vintage Prophets with modern sequencing capabilities. It's ideal for serious sound designers, composers, and players who want a versatile, expressive, and deeply satisfying instrument. This is a premium-priced synth that justifies its cost with its sonic depth and build quality.
Pros
- Curtis filters deliver that classic, creamy Prophet sound.
- Dual oscillator architecture allows for incredibly rich, evolving tones.
- The polyphonic step sequencer is a game-changer for composing sequences.
Cons
- The 5-octave keyboard might be limiting for some performers.
- The extensive feature set has a steeper learning curve than simpler synths.
51AudioFu
Index↑ 7.1%since Aug 14$3,233 · Aug 14$3,462 now$3,462€3,089 at Thomann · in stockCheck price ↗ -
- Weight3.97 kg
This steel-bodied synth sounds like the classic Prophet models you love, with that warm, resonant filter. It packs four voices and aftertouch for serious work, but the small keyboard and limited polyphony keep it simple. Perfect for studio use or small gigs where you need that vintage analog punch.
Pros
- Steel housing gives it a solid, professional feel.
- Prophet-style resonance filter adds authentic analog warmth.
- Polyphonic aftertouch lets you shape notes dynamically.
Cons
- Only 37 keys limits use on larger stages.
- Four voices feels restrictive for complex arrangements.
All 12 general synthesizers
Same index, same nightly prices — compact. Colour options of one model share a row. Tap a photo to zoom.
- 11
Sequential Prophet-6 49-Key 6-Voice Polyphonic SynthesizerProphet 6 Case Set · Sequential36↑ 11.1%$4,369€3,899$4,369€3,899Check ↗
- 12
Sequential Prophet 5 Headphone BundleSequential22↑ 7.0%$4,313€3,849$4,313€3,849Check ↗
General Synthesizers by the numbers
Measured across all 241 models we track, not a sample.
Median $4,145 — half of all general synthesizers here cost less.
median of 182 models · 1.12 kg–15 kg
most common · 38 models
median of 21 models · 25–88
How to choose the best general synthesizers
Heritage & Sound
Sequential synths carry a sonic signature - a warmth and richness that's instantly recognizable, largely thanks to their analog filters. It's not a sterile, digital sound; it's got that subtle harmonic complexity that makes things feel alive. Think creamy pads, punchy basses, and leads with serious character.
Sequential's Filter Design
Their filters are the heart of their sound. They've refined the classic Prophet filter design over the years, offering a sweet spot between aggressive resonance and smooth, musicality. It's a filter that responds beautifully to subtle changes in modulation, giving you incredible expressive control.
Modulation Capabilities
Sequential synths aren't just about presets; they're built for sound design. The LFOs and envelopes are deep and versatile, allowing for complex, evolving textures. Being able to really shape the sound over time is crucial for cutting through the mix in a band setting.
Build Quality & Ergonomics
These are solid instruments. The keybeds feel great, the knobs are smooth and responsive, and the overall construction inspires confidence. It's the kind of gear you want to trust on stage, night after night.
User Interface
Sequential has generally kept things straightforward, prioritizing usability over endless menus. While there's depth to be explored, the learning curve isn't steep, letting you focus on making music rather than deciphering cryptic manuals.
Buying guide
So, you're diving into the Sequential world? Smart move. They've got a lineage stretching back to the Prophet-5, a synth that practically defined modern electronic music. But Sequential isn't just about history; they're building incredible instruments today, blending vintage mojo with modern features, and consistently delivering sounds that cut through a mix. Let's break down their current lineup and figure out which one fits your needs - whether you're crafting cinematic soundscapes or just need a killer bassline for your band.
Don't chase the biggest feature list; chase the sound that inspires you. The smaller Prophet-6 is a fantastic entry point, but the Peak offers more voices and a more aggressive character. Consider your workflow - do you need immediate hands-on control, or are you comfortable with a more menu-driven approach?
And honestly, the price premium for a Sequential is real; you're paying for the heritage, the build quality, and that signature Sequential tone.
How the AudioFu Index works
Five measured signals and nothing else — no stars from strangers, no “tested by experts” we didn’t do. The weights are fixed and public. We don’t play these instruments; we measure the market around them.
This chart covers 14 general synthesizers from the Thomann catalogue (of 241 in the category). Before you buy, read hands-on reviews and, where you can, play it. Full methodology.
AudioFu earns a commission when you buy through our Thomann links. It never changes the order — the index does.
- Demand40%
How many of this exact model are for sale on Reverb right now — what musicians actually buy and resell.
- Lineup20%
How many finishes Thomann stocks — makers expand the models that sell.
- Price15%
Where the price has moved since we started tracking in August.
- Specs15%
How completely the maker documents it.
- Maker10%
How deep the brand’s range is in this category.
Questions
Are Sequential synths difficult to program?
Not really. While they have deep modulation options, the interface is generally well-laid out and intuitive. The factory patches are a great starting point, and you'll be tweaking sounds in no time.
How do Sequential synths compare to Moog?
Both are legendary, but they have distinct personalities. Moog is often associated with a more raw, aggressive sound, while Sequential leans towards warmth and richness. It really comes down to personal preference and the specific sound you're after.
Do I need an external sequencer?
The synths have onboard sequencers, but for more complex arrangements, an external sequencer (hardware or software) can be incredibly useful. It's a nice-to-have, not a necessity.
What's the deal with the 'Prophet' name?
'Prophet' is the lineage. The original Prophet-5 was a game-changer, and Sequential continues to build on that legacy with their modern instruments. It's more than just a name; it represents a specific sonic aesthetic.
Are Sequential synths prone to issues?
Like any complex electronic instrument, they can have occasional hiccups. However, Sequential's build quality is generally excellent, and they've addressed many early issues with firmware updates. Proper care and maintenance are always key.
